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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
11.21
Human Site:
Y398
Identified Species:
18.97
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
Y398
V
P
P
P
L
L
H
Y
P
P
P
A
K
V
P
Chimpanzee
Pan troglodytes
XP_509441
819
90122
L360
V
P
P
P
A
T
A
L
N
P
P
A
P
P
T
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
Dog
Lupus familis
XP_546925
857
93734
Y398
V
P
P
P
L
F
Q
Y
P
A
L
A
K
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
F403
G
P
T
P
L
L
P
F
P
T
P
V
K
V
H
Rat
Rattus norvegicus
Q6AXT8
471
49872
L51
P
Y
F
M
K
N
H
L
G
S
Y
E
C
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
Y419
K
P
K
P
L
L
Q
Y
G
F
P
S
K
C
L
Frog
Xenopus laevis
NP_001084764
548
60887
R128
L
Q
W
R
D
K
I
R
L
N
N
A
I
W
R
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
Y382
G
P
S
Y
Q
Q
P
Y
M
P
L
F
T
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
Q386
Q
H
Q
Q
Q
N
H
Q
Q
Q
Q
L
Q
T
A
Honey Bee
Apis mellifera
XP_394429
1014
115124
S524
L
P
P
V
A
P
I
S
T
K
P
Y
K
V
V
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
T405
M
D
Y
R
L
M
P
T
R
Q
S
S
A
I
T
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
Q538
Q
Q
N
E
V
I
N
Q
Y
L
P
L
Q
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
T611
P
T
P
P
L
A
S
T
S
H
A
S
P
E
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
46.6
0
66.6
N.A.
53.3
6.6
N.A.
N.A.
46.6
6.6
20
N.A.
6.6
33.3
6.6
13.3
P-Site Similarity:
100
46.6
0
66.6
N.A.
60
6.6
N.A.
N.A.
53.3
13.3
20
N.A.
13.3
40
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
15
8
8
0
0
8
8
29
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
0
0
0
8
0
15
0
% E
% Phe:
0
0
8
0
0
8
0
8
0
8
0
8
0
0
0
% F
% Gly:
15
0
0
0
0
0
0
0
15
0
0
0
0
8
0
% G
% His:
0
8
0
0
0
0
22
0
0
8
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
8
15
0
0
0
0
0
8
8
0
% I
% Lys:
8
0
8
0
8
8
0
0
0
8
0
0
36
8
0
% K
% Leu:
15
0
0
0
43
22
0
15
8
8
15
15
0
0
15
% L
% Met:
8
0
0
8
0
8
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
15
8
0
8
8
8
0
0
0
0
% N
% Pro:
15
50
36
43
0
8
22
0
22
22
43
0
15
8
22
% P
% Gln:
15
15
8
8
15
8
15
15
8
15
8
0
15
0
15
% Q
% Arg:
0
0
0
15
0
0
0
8
8
0
0
0
0
0
8
% R
% Ser:
0
0
8
0
0
0
8
8
8
8
8
22
0
0
0
% S
% Thr:
0
8
8
0
0
8
0
15
8
8
0
0
8
8
15
% T
% Val:
22
0
0
8
8
0
0
0
0
0
0
8
0
29
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
8
8
0
0
0
29
8
0
8
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _